As at 21 March 2017, the Company is aware of the following holdings of 3% or more of the voting rights in its shares.
|BlueFocus International Limited||19.443%||63,199,369|
|Aberforth Partners LLP||16.07%||52,797,322|
|J O Hambro Capital Management Limited||6.10%||20,030,402|
|The Wellcome Trust Limited as a Trustee of The Wellcome Trust||5.0815%||16,683,109|
|Aberdeen Asset Managers Limited||5.0%||16,144,060|
|Miton Group plc||4.74%||15,566,665|
* Percentages are based on date of notification as opposed to current issued share capital figure.